Effects of Glucose Levels on Glucose Consumption and Viability of Chondrocytes and Intervertebral Disc Cells

نویسنده

  • Garrett R. Waggoner
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Noscapine on Oxygen-Glucose Deprivation on Primary Murine Cortical Neurons in High Glucose Condition

AbstractIn the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µM) in presence of D-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. Cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by MTT assay, the modified Griess method and Fura-2 respectively. 25 and 100...

متن کامل

The Effect of Noscapine on Oxygen-Glucose Deprivation on Primary Murine Cortical Neurons in High Glucose Condition

AbstractIn the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µM) in presence of D-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. Cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by MTT assay, the modified Griess method and Fura-2 respectively. 25 and 100...

متن کامل

Effect of Dynamic Compression on ATP Production and Release by Intervertebral Disc Cells

INTRODUCTION Intervertebral disc (IVD) degeneration is known to affect millions of individuals every year but mechanisms involved in IVD degeneration are not fully understood [1]. Cellular biosynthesis of extracellular matrix, which is important for maintaining the integrity of tissue and preventing tissue degeneration, is an energy demanding process. Adenosine triphosphate (ATP), the major ene...

متن کامل

Oxygen Consumption Rate of Human Intervertebral Disc Cells

INTRODUCTION The intervertebral disc (IVD) is the largest avascular structure in the human body, and is comprised of three major components: the annulus fibrosus (AF), nucleus pulposus (NP), and cartilaginous end-plate (CEP). Compromised disc nutrition is believed to be the key factor in the development of disc degeneration which has hampered previous tissue engineering or repair efforts. The b...

متن کامل

Distinct effects of royal jelly on human endothelial cells under high glucose condition

To assess different effects of royal Jelly in protecting the human endothelial cells from high glucose level, human umbilical vein endothelial cells were exposed to various concentrations of royal jelly, from 0.625 to 10 mg/ml, at the presence of 5 and 30 mM glucose contents over a course of 72 h. In addition to cell viability assessment by conventional MTT assay, we also analyzed the feature o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017